Table 2 Differential metabolites between SM and FSM

Alcohols and polyols

6β, 11α Dihydroxyprogesterone

347.22

369.7

3.65

6.29E-03

1.23

↑

Inulobiose

325.11

404.8

1.96

5.77E-03

1.23

↑

13,14-Dihydro-15-keto-PGE2

353.23

384.9

-1.83

2.17E-05

1.31

↓

Amines

Plant Sphingosine

318.3

450.8

3.61

6.64E-05

1.31

↑

Spermidine

146.17

45.8

-1.64

1.18E-05

1.31

↓

Oleoyl ethanolamide

326.31

513.8

-1.74

2.42E-02

1.15

↓

Amino acids, peptides, and analogues

L-Lysine

147.11

46.1

4.75

1.77E-02

1.27

↑

N-acetyl Citrulline

217.11

285.1

4.65

3.45E-05

1.31

↑

N-acetyl Histidine

198.08

55.3

3.59

1.97E-05

1.31

↑

Saccharopine

277.14

55.2

3.07

6.05E-04

1.29

↑

Histidine

154.06

52.3

2.69

3.73E-05

1.29

↑

Phenylalanine

166.09

93

2.27

2.43E-03

1.26

↑

Threonine

120.07

52.6

1.86

5.05E-05

1.31

↑

N6 Acetyl L-lysine

187.11

74.3

1.85

1.71E-04

1.28

↑

N-acetyl Glutaric acid

188.06

48.6

0.61

4.27E-02

1.07

↑

Diaminopimelic acid

191.1

52.9

0.61

3.20E-02

1.12

↑

γ- Glutamyl alanine

219.1

56.6

0.57

4.24E-03

1.24

↑

Homoserine

100.04

45.6

0.29

2.17E-02

1.14

↑

N-acetylornithine

175.11

54

-0.87

4.55E-03

1.3

↓

Tyrosine

182.08

105

-0.56

1.68E-04

1.3

↓

Proline

116.03

52.3

-6.29

4.49E-06

1.31

↓

Glutamate

148.06

52.9

-1.35

2.46E-03

1.26

↓

Aspartic acid

134.05

52.9

-3.4

7.99E-05

1.31

↓

Arginine

173.1

64.4

-0.5

4.32E-03

1.23

↓

Asparagus cochinchinensis

295.13

296.8

-3.03

5.94E-05

1.31

↓

4,5-dihydro Orotic acid acid

158.96

228.1

-1.02

3.17E-02

1.12

↓

Benzoic acids and derivatives

Formylaminosalicylic acid

166.05

164.2

0.61

9.22E-03

1.21

↑

Toluate

135.04

375.3

-3.07

2.43E-02

1.24

↓

Phthalate

165.04

551.2

-4.82

8.40E-03

1.2

↓

2-pyrocatechuic acid

153.02

245.1

-6.34

7.79E-03

1.28

↓

Carbohydrates and carbohydrate conjugates

Sucrose

343.3

412.2

3.67

1.03E-02

1.2

↑

Mannitol

181.07

51.1

2.57

1.30E-03

1.26

↑

D-Glucose 1-phosphate

259.02

45.6

2.2

8.29E-04

1.27

↑

Trehalose

341.11

51.7

-1.44

1.17E-03

1.26

↓

Sorbitol

182.98

454.3

-2.55

2.49E-03

1.31

↓

Ribitol

151.06

52.3

-1.34

3.70E-04

1.28

↓

Melezitose

504.17

355.3

-3.11

1.26E-07

1.32

↓

Gluconic acid

195.05

48.4

-1.46

1.21E-05

1.3

↓

Galactaric acid

209.03

44.9

-1.48

1.08E-03

1.27

↓

D-Xylose

151.1

595.1

-2.32

2.35E-03

1.26

↓

D-Arabitol

152.07

105.2

-3.34

2.73E-04

1.3

↓

Benzenediols

Norepinephrine

169.98

392

-1.78

3.31E-02

1.12

↓

Hydroquinone

110.02

392

-1.15

1.28E-02

1.19

↓

Epinephrine

184.1

116

0.23

7.84E-03

1.22

↑

Fatty acids and conjugated fatty acids

Heptanoic acid

113.06

211.5

5.65

1.39E-04

1.32

↑

12,13-DHOME

315.25

472.4

1.06

1.63E-03

1.27

↑

Palmitoleic acid

237.22

620.3

-3.02

9.11E-03

1.29

↓

5-Hydroxypentanoic acid

118.07

445.7

-1.09

3.35E-03

1.25

↓

Lineolic acids and derivatives

Methyl jasmonate

207.14

541.5

4.3

1.49E-05

1.31

↑

Alpha-Linolenic acid

261.22

682.5

3.96

3.93E-05

1.31

↑

9-OxoODE

294.21

500.2

1.19

1.22E-02

1.2

↑

(-)-Jasmonic acid

193.12

276.6

0.58

2.10E-03

1.26

↑