Fig. 6

Exhibits the molecular mechanism of okra and CD. Abbreviations: Â↑= Increase, ↓=Decrease, PI3K=Phosphoinositide 3-kinase, AKT=protein kinase B, GS =glycogen synthase, ROS = Reactive Oxygen Species, TNF-α=tumor necrosis factor-α. IL-1β=interleukin-1β, IL-6=interleukin 6, IFN-γ=interferon-gamma, GSK3β=Glycogen synthase kinase-3 beta, pGSK3β = phosphorylated glycogen synthase kinase-3 beta, DPP4=Dipeptidyl peptidase-4 inhibitor, MDA=Malondialdehide, NMDA=The N-methyl-D-aspartate, Aβ=Amyloid beta, GSH=Glutathione peroxidase, SOD=Superoxide dismutase, BDNF= Brain-derived neurotropic factor, CREB=Cyclic-AMP response element binding, pGSK3β=Phosphorylated Glycogen Synthase Kinase 3β, CD=cognitive dysfunction.